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Dot1L Inhibitor 13

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SL-2675

Dot1L Inhibitor 13, >98% (HPLC)

CAS No. : [1940206-71-2]

IUPAC Name : N4-Methyl-N2-(2-methyl-1-(2-((3-methyl-3H-imidazo[4,5-b]pyridin-6-yl)oxy)phenyl)-1H-indol-6-yl)pyrimidine-2,4-diamine

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5MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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50MGRequest A Quote
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500MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
We accept
Note: SL-2675 is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C27H24N8O
Mol. Weight :
476.53
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SL-2675 is a potent, selective and orally bioavailable inhibitor of Dot1L with an IC50 and Ki of 0.4 nM and 0.08 nM, respectively.

References : Chen C. et al.: ACS Med. Chem. Lett., 7(8), 735-740, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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