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Droperidol

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Droperidol, >98%

CAS No. : [548-73-2]

Synonyms : Dehydrobenzperidol

IUPAC Name : 1-(1-(4-(4-Fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one

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Chemical Properites
Mol. Formula :
C22H22FN3O2
Mol. Weight :
379.44
Appearance :
Solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Droperidol is a butyrophenone dopamine-2 receptor antagonist that blocks the activation of GABA(A) receptors and neuronal nicotinic receptors (nAChR), showing IC50 values of 12.6 nM and 5.8 μM, respectively. It is known for its anesthetic and sedative effects.

References : Pamela F. et al.: Anesthesiology, 96(4), 987-93, 2002; Yelnosky J. et al.: Toxicol Appl Pharmacol., 5, 37-47, 1964.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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