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DS-9300

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SI-7226

DS-9300, >98% (HPLC)

CAS No. : [2259641-46-6]

IUPAC Name : (2R,4R)-1-(4,4-Difluoro-1-(4-methoxyphenyl)cyclohexane-1-carbonyl)-4-fluoro-N-(1H-pyrazolo[4,3-b]pyridin-7-yl)pyrrolidine-2-carboxamide

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Chemical Properites
Mol. Formula :
C25H26F3N5O3
Mol. Weight :
501.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : DS‑9300 selectively inhibits EP300/CBP HAT activity with nanomolar potency (IC50 = 28 nM) and displays notable anticancer effects. It is suitable for exploring EP300/CBP‑dependent pathways in prostate cancer models.

References : Kanada R. et al.: J. Med. Chem., 66(1), 695-715, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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