DSM 265

SI-5532

DSM 265, >98% (HPLC)

CAS No. : [1282041-94-4]

MDL No. : MFCD28502125

IUPAC Name : 2-(1,1-Difluoroethyl)-5-methyl-N-(4-(pentafluoro-λ6-sulfaneyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Price And Availability
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25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : DSM265 is a long-duration inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 of 8.9 nM. DSM265 can also inhibit the growth of Pf3D7 parasites with an EC50 of 4.3 nM.

References : Kokkonda S. et al.: J. Med Chem., 59(11), 5416-31, 2016; Phillips M. A. et al.: Sci Transl Med., 7(296), 296ra111, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.