Durlobactam sodium

SI-5740

Durlobactam sodium, >98% (HPLC)

CAS No. : [1467157-21-6]

Synonyms : ETX-2514 sodium

IUPAC Name : Sodium (2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl sulfate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: Durlobactam sodium is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : Durlobactam sodium is a β-lactamase inhibitor drug candidate. Sulbactam-durlobactam (formerly sulbactam-ETX2514) (SUL-DUR) is a β-lactam/β-lactamase inhibitor combination antibiotic designed to treat serious infections caused by ABC, including multidrug-resistant (MDR) strains. SUL-DUR had a MIC50/MIC90 of 1/2 μg/ml compared to a MIC50/MIC90 of 8/64 μg/ml for sulbactam alone.

References : Rodvold K. A. et al.: Antimicrob Agents Chemother., pii: AAC.01089-18, 2020; Iyer R. et al.: ACS Infect Dis., 4(3), 373-381, 2018; McLeod S. M. et al.: Antimicrob Agents Chemother., 62(2). pii: e01576-17, 2018; Shapiro A. B. et al.: ACS Infect Dis., 3(11), 833-844, 2017; Durand-Reville T. F. et al.: Nat Microbiol., 2, 17104, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.