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Dutasteride impurity H

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Dutasteride impurity H, >98%

IUPAC Name : (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(2,5-Bis(trifluoromethyl)phenyl)-1-((4aR,4bS,6aS,7R,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carbonyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C46H55F6N3O4
Mol. Weight :
827.95
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Dutasteride, which is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT.

References : Lazier C. B. et al.: Prostate, 58(2), 130-44, 2004; Biancolella M. et al.: Invest New Drugs, 25(5), 491-7, 2007; Bramson H. N. et al.: J. Pharmacol Exp Ther. 282(3), 1496-502, 1997; Andriole G. L. et al.: J. Urol., 175(5), 1657-62, 2006;
Margiotta-Casaluci L. et al.: Aquat Toxicol., 128-129, 113-23, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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