E-6201

SI-6431

E-6201, >98% (HPLC)

CAS No. : [603987-35-5]

IUPAC Name : (3S,4R,5Z,8S,9S,11E)-14-(Ethylamino)-8,9,16-trihydroxy-3,4-dimethyl-3,4,9,10-tetrahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : E-6201 selectively inhibits MEK1 and MEKK1 with high potency and reduces LPS‑induced TNFα transcription (IC₅₀ = 50 nM). Its dual‑kinase activity makes it a valuable tool for dissecting MAPK‑mediated inflammatory responses.

References : Goto M. et al.: J. Pharmacol. Exp. Ther., 331(2), 485-95, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.