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SL-1442
E7449, >98%
CAS No. : [1140964-99-3]
MDL No. : MFCD28167842
IUPAC Name : 8-(Isoindolin-2-ylmethyl)-1H-pyridazino[3,4,5-de]quinazolin-3(2H)-one
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C18H15N5O | Mol. Weight : 317.34 |
Appearance : Light yellow solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : E7449 is an orally bioavailable, potent, small molecule inhibitor of PARP1 and PARP2; enhances the efficacy of radiotherapy and chemotherapy and has potent single agent anticancer activity in BRCA-deficient tumors.
References : McGonigle S. et al:. Oncotarget., 6(38), 41307, 2015.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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