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EAI045

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SI-5695

EAI045, >98% (HPLC)

CAS No. : [1942114-09-1]

MDL No. : MFCD30187871

IUPAC Name : 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide

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1GRequest A Quote
Back Order  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C19H14FN3O3S
Mol. Weight :
383.40
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR, developing for the potential treatment of non-small cell lung cancer (NSCLC).

References : Jia Y. et al.: Nature 534(7605), 129-32, 2016; Wang S. et al.: Cancer Lett., 385, 51-54, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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