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EBP-IN-1

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SI-7596

EBP-IN-1, >98% (HPLC)

CAS No. : [3034437-44-7]

IUPAC Name : 3-(4-Cyclopropylphenyl)-1-ethyl-8-((tetrahydro-2H-pyran-4-yl)methyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione

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Chemical Properites
Mol. Formula :
C24H33N3O3
Mol. Weight :
411.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This crosses the blood–brain barrier and inhibits EBP sterol isomerase activity, producing Zymostenol buildup and demonstrating strong brain target binding after repeated administration. It inhibits human ERG channels (IC50 = 8.2 µM) and promotes oligodendrocyte generation in human cortical organoids, making it a valuable tool for multiple sclerosis research.

References : Dorel R. et al.: J. Med. Chem., 67(6), 4819-4832, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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