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Edecesertib

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SI-7515

Edecesertib, >98% (HPLC)

CAS No. : [2408839-73-4]

Synonyms : GS-5718

IUPAC Name : 4-(((R)-1-Cyanoethyl)amino)-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-((R)-2-fluoro-3-hydroxy-3-methylbutyl)nicotinamide

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Chemical Properites
Mol. Formula :
C22H22FN7O2
Mol. Weight :
435.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Edecesertib selectively targets IRAK4 with oral activity and effectively dampens TLR/MYD88‑driven inflammatory signaling. Its strong anti‑inflammatory profile supports its use in models of rheumatoid arthritis and lupus.

References : Feng Y. et al.: Acta. Pharmaceutica. Sinica. B., 14(12), 5091-5105, 2024;Kalliolias G. D. et al.: Biomedicines, 12(1), 138, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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