EEDi-5273

SI-6801

EEDi-5273, >98% (HPLC)

CAS No. : [2585648-55-9]

Synonyms : APG-5918

IUPAC Name : 12-(((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-4-isopropyl-7-(trifluoromethyl)-4,5-dihydro-3H-2,4,8,11,12a-pentaazabenzo[4,5]cycloocta[1,2,3-cd]inden-3-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : EEDi‑5273 selectively targets the EED subunit of PRC2 with sub‑nanomolar potency (IC50 = 0.2 nM), effectively blocking H3K27me3 deposition. Its strong epigenetic and antiproliferative effects make it valuable for investigating PRC2‑driven cancers such as ovarian cancer.

References : Rej. R.K. et al.: J. Med. Chem., 64(19), 14540-14556, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.