EF-4-177

SI-7231

EF-4-177, >98% (HPLC)

CAS No. : [2891574-93-7]

IUPAC Name : 2-((2-(6-Cyano-1H-indol-3-yl)ethyl)amino)-5-(pentafluoro-l6-sulfaneyl)benzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : EF‑4‑177 allosterically inhibits CDK2 with nanomolar potency (IC₅₀ = 87 nM) and demonstrates strong activity in disrupting spermatogenesis, making it valuable for probing CDK2‑regulated reproductive processes.

References : Faber E. B. et al.: J. Med. Chem., 66(3), 1928-1940, 2023; Huang Y. et al.: Eur. J. Med. Chem., 275, 116547, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.