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EGFR inhibitor

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SI-6785

EGFR inhibitor, >98% (HPLC)

IUPAC Name : (2-((5-Chloro-2-((2-methoxy-4-morpholino-5-(1H-pyrazol-5-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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25MGRequest A Quote
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50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C26H29ClN7O3P
Mol. Weight :
553.99
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : A potent EGFR inhibitor that demonstrates improved cellular activity, oral exposure, and in vivo efficacy in EGFR‑mutant disease models, including Exon19 del/T790M/C797S triple‑mutant xenografts.

References : Finlay M. R. V. et al.: J. Med. Chem., 64(18), 13704−13718, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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