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Elacridar hydrochloride

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SI-6208

Elacridar hydrochloride, >98% (HPLC)

CAS No. : [143851-98-3]

Synonyms : GF-120918 hydrochloride

IUPAC Name : N-(4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-5-methoxy-9-oxo-9,10-dihydroacridine-4-carboxamide hydrochloride

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Chemical Properites
Mol. Formula :
C34H33N3O5 • HCl
Mol. Weight :
600.11
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Elacridar hydrochloride is a potent, orally active P‑gp/BCRP inhibitor used to probe the role of efflux transporters in limiting drug delivery to the brain. It is also a valuable tool compound for research on cancer biology and resistance pathways.

References : Sane R. et al.: Drug Metab Dispos., 40(8), 1612-9, 2012; Sato H. et al.: Eur. J. Pharmacol., 746, 258-66, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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