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Elafibranor

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SI-6098

Elafibranor, >98% (HPLC)

CAS No. : [923978-27-2]

Synonyms : GFT-505

IUPAC Name : (E)-2-(2,6-Dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid

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25MGRequest A Quote
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Chemical Properites
Mol. Formula :
C22H24O4S
Mol. Weight :
384.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Elafibranor activates PPARα and PPARδ with EC50 values of 45 nM and 175 nM, respectively. It is widely used as a tool compound for investigating PPAR‑mediated regulation in primary biliary cholangitis.

References : Liu Z. M. et al.: Expert. Opin. Investig. Drugs, 24(5), 611-21, 2015; Ratziu V. et al.: Gastroenterology, 150(5), 1147-1159, 2016; Hanf R. et al.: Diab. Vasc. Dis. Res., 11(6), 440-7, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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