Elagolix impurity C

SL-8191

Elagolix impurity C, >98%

CAS No. : [1150560-46-5]

Related CAS No. : [832720-84-0] of the free base compound

IUPAC Name : Ethyl 4-(((1R)-2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)-1-phenylethyl)amino)butanoate hydrochloride

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Applications : This is an impurity of Elagolix, which is a human GnRH receptor (GnRHR) antagonist. Elagolix is used for the treatment of moderate to severe pain associated with endometriosis.

References : Kim S. M. et al.: J. Med. Chem., 59(19), 9150-9172, 2016; Chen C. et al. J. Med. Chem., 51(23), 7478-85, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.