Elagolix impurity D

SL-8192

Elagolix impurity D, >98%

CAS No. : [1062642-62-9]

Synonyms : Elagolix N-methyl impurity

IUPAC Name : 5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-((R)-2-(methylamino)-2-phenylethyl)pyrimidine-2,4(1H,3H)-dione

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Applications : This is an impurity of Elagolix, which is a human GnRH receptor (GnRHR) antagonist. Elagolix is used for the treatment of moderate to severe pain associated with endometriosis.

References : Kim S. M. et al.: J. Med. Chem., 59(19), 9150-9172, 2016; Chen C. et al. J. Med. Chem., 51(23), 7478-85, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.