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Eletriptan-d5

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SL-10498

Eletriptan-d5, >98%

CAS No. : [1126745-65-0]

Synonyms : UK-116044-d5

IUPAC Name : (R)-3-((1-(Methyl-d3)pyrrolidin-2-yl-5,5-d2)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole

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Chemical Properites
Mol. Formula :
C22H21D5N2O2S
Mol. Weight :
387.55
Appearance :
Solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Eletriptan-d5 is a deuterium labelled version of Eletriptan. This can be used as an analytical labelled reference standard. Eletriptan is an orally active, highly selective agonist for serotonin 5-HT1B and 5-HT1D receptors. Eletriptan suppresses neurogenic inflammation markers in rats, making it useful for migraine research.

References : McCormack P. L. et al.: Drugs 66(8), 1129-49, 2006; Willems E. et al.: Naunyn Schmiedebergs Arch Pharmacol., 358(2), 212-9, 1998.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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