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Elexacaftor

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SI-6421

Elexacaftor, >98% (HPLC)

CAS No. : [2216712-66-0]

Synonyms : VX-445

IUPAC Name : (S)-N-((1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide

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Chemical Properites
Mol. Formula :
C26H34F3N7O4S
Mol. Weight :
597.66
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Elexacaftor promotes the proper processing and trafficking of CFTR, elevating surface expression of the protein. Its corrective activity makes it a key component in CFTR‑modulator research.

References : Keating D. et al.: N. Engl. J. Med., 379(17), 1612-1620, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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