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Eliglustat hemitartrate

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SL-1816

Eliglustat hemitartrate, >99%

CAS No. : [928659-70-5]

MDL No. : MFCD22665712

Synonyms : Genz-112638

IUPAC Name : N-((1R,2R)-1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)octanamide hemi((2R,3R)-2,3-dihydroxysuccinate)

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Chemical Properites
Mol. Formula :
C23H36N2O4 . 1/2C4H4O5
Mol. Weight :
479.58
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Eliglustat is a specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.

References : McEachern K. A. et al.: Mol. Genet. Metab., 91(3), 259-268, 2007; Shayman J. A. Drugs Future 35(8), 613-620, 2010; Nelson S. Yew. et al. PLoS One 5(6), e11239, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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