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Synonyms : BAY-1895344 hydrochloride
IUPAC Name : (R)-3-Methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine hydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H21N7O • HCl | Mol. Weight : 411.89 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Elimusertib hydrochloride selectively inhibits ATR with nanomolar potency (IC50 = 7 nM) and displays robust antitumor efficacy. Its activity across solid tumor and lymphoma models makes it a valuable tool for probing ATR‑regulated DNA repair pathways and therapeutic vulnerabilities.
References : Luecking T. U. et al.: Cancer Research., 77(13), 2017; Wengner M. A. et al.: Cancer Research, 77(13), 2017; Lucking U. et al.: J. Med. Chem., 63(13), 7293-7325, 2020.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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