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ELN-582646

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SI-6381

ELN-582646, >98% (HPLC)

IUPAC Name : (R)-7-Ethyl-2-(2-(4-fluorophenyl)-1H-imidazol-1-yl)-5-methyl-8-(1-methyl-1H-pyrazol-3-yl)-7,8-dihydropteridin-6(5H)-one

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
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25MGRequest A Quote
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50MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H21FN8O
Mol. Weight :
432.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ELN‑582646 is a potent, selective PLK2 inhibitor, closely related to ELN‑582175, and used as a tool compound for probing PLK2‑dependent signaling, neuronal homeostasis, and centrosomal regulation. It provides robust biochemical PLK2 inhibition with minimal off‑target activity, supporting studies in neurodegeneration and cell‑cycle biology.

References : Fitzgerald K. et al.: Toxicol Appl. Pharmacol., 269(1), 1-7, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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