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Elpipodect

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SI-7224

Elpipodect, >98% (HPLC)

CAS No. : [1424371-93-6]

Synonyms : MK-8189

IUPAC Name : 2-Methyl-N-((5-methyl-1,3,4-thiadiazol-2-yl)methyl)-6-(((1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)pyrimidin-4-amine

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Chemical Properites
Mol. Formula :
C19H22N6OS
Mol. Weight :
382.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Elpipodect selectively inhibits PDE10A with picomolar potency (Ki = 29 pM) and is orally active. It is valuable for probing PDE10A‑related mechanisms in schizophrenia research.

References : Layton M. E. et al.: J. Med. Chem., 66(2), 1157-1171, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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