Emavusertib

SI-6348

Emavusertib, >98% (HPLC)

CAS No. : [1801344-14-8]

Synonyms : CA-4948

IUPAC Name : (R)-N-(5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Emavusertib potently inhibits IRAK4 and FLT3, leading to suppression of NF‑κB/MyD88 signaling and decreased IL‑6 and IL‑10 release. These activities contribute to its anti‑inflammatory profile and its ability to inhibit cancer‑cell proliferation and promote apoptosis. It shows clear antitumor activity in vivo.

References : Wiese M. D. et al.: Expert. Opin. Investig. Drugs, 1-8, 2020; Guidetti F. et al.: J. Clin. Med., 12(2), 399, 2023; Parrondo R. D. et al.: Front Immunol., 14, 1239082, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.