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Emavusertib

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SI-7516

Emavusertib, >98% (HPLC)

CAS No. : [1801344-14-8]

Synonyms : CA-4948

IUPAC Name : (R)-N-(5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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50MGRequest A Quote
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We accept
Chemical Properites
Mol. Formula :
C24H25N7O5
Mol. Weight :
491.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Emavusertib selectively inhibits IRAK4 and FLT3 with oral activity, suppressing NF‑κB/MyD88 signaling and lowering IL‑6 and IL‑10 production. These effects translate into anti‑inflammatory and anti‑proliferative responses, culminating in apoptosis and measurable antitumor activity in vivo.

References : Wiese M. D. et al.: Expert. Opin. Investig. Drugs, 29(5), 475-482, 2020; Guidetti F. et al.: J. Clin. Med., 12(2), 399, 2023; Parrondo R. D. et al.: Front. Immunol., 14, 1239082, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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