Emavusertib hydrochloride

SI-6349

Emavusertib hydrochloride, >98% (HPLC)

CAS No. : [2376399-42-5]

Synonyms : CA-4948 hydrochloride

IUPAC Name : (R)-N-(5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Emavusertib hydrochloride is an orally active inhibitor of IRAK4 and FLT3 that suppresses NF‑κB/MyD88 signaling and lowers IL‑6 and IL‑10 levels. These activities contribute to its anti‑inflammatory profile and its ability to inhibit tumor‑cell proliferation and induce apoptosis. It shows robust antitumor efficacy in vivo.

References : Wiese M. D. et al.: Expert. Opin. Investig. Drugs, 1-8, 2020; Guidetti F. et al.: J. Clin. Med., 12(2), 399, 2023; Parrondo R. D. et al.: Front Immunol., 14, 1239082, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.