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Emavusertib maleate

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SI-7517

Emavusertib maleate, >98% (HPLC)

CAS No. : [2376399-39-0]

Synonyms : CA-4948 maleate

IUPAC Name : (R)-N-(5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide maleate

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C24H25N7O5 • C4H4O4
Mol. Weight :
607.58
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Emavusertib maleate is the maleate salt of the orally active IRAK4/FLT3 inhibitor Emavusertib. It suppresses NF‑κB/MyD88 signaling and lowers IL‑6 and IL‑10 levels, producing anti‑inflammatory and anti‑proliferative responses that culminate in apoptosis and measurable antitumor activity in vivo.

References : Wiese M. D. et al.: Expert. Opin. Investig. Drugs, 29(5), 475-482, 2020; Guidetti F. et al.: J. Clin. Med., 12(2), 399, 2023; Parrondo R. D. et al.: Front. Immunol., 14, 1239082, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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