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CAS No. : [2376399-39-0]
Synonyms : CA-4948 maleate
IUPAC Name : (R)-N-(5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide maleate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C24H25N7O5 • C4H4O4 | Mol. Weight : 607.58 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Emavusertib maleate is the maleate salt of the orally active IRAK4/FLT3 inhibitor Emavusertib. It suppresses NF‑κB/MyD88 signaling and lowers IL‑6 and IL‑10 levels, producing anti‑inflammatory and anti‑proliferative responses that culminate in apoptosis and measurable antitumor activity in vivo.
References : Wiese M. D. et al.: Expert. Opin. Investig. Drugs, 29(5), 475-482, 2020; Guidetti F. et al.: J. Clin. Med., 12(2), 399, 2023; Parrondo R. D. et al.: Front. Immunol., 14, 1239082, 2023.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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