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SI-5709

EMPA, >98% (HPLC)

CAS No. : [680590-49-2]

MDL No. : MFCD23381172

IUPAC Name : N-Ethyl-2-((N-(6-methoxypyridin-3-yl)-2-methylphenyl)sulfonamido)-N-(pyridin-3-ylmethyl)acetamide

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Chemical Properites
Mol. Formula :
C23H26N4O4S
Mol. Weight :
454.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : EMPA is a high-affinity, reversible and selective orexin 2 (OX2) receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively.

References : Malherbe P. et al.: Br. J. Pharmacol., 156(8), 1326-1341, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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