Emvododstat

SI-6535

Emvododstat, >98% (HPLC)

CAS No. : [1256565-36-2]

Synonyms : PTC-299

IUPAC Name : 4-Chlorophenyl (S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indole-2-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Emvododstat selectively inhibits VEGFA mRNA translation, reducing VEGF protein levels through a post‑transcriptional mechanism, and also potently inhibits DHODH. With good oral bioavailability and minimal off‑target or myelosuppressive liabilities, PTC299 is well suited for studies exploring angiogenesis, nucleotide biosynthesis, and hematologic cancer biology.

References : Cao L. et al.: Mol. Cancer Ther., 18(1), 3-16, 2019; Bender Ignacio R. A. et al.: J. Acquir Immune Defic. Syndr., 72(1), 52-7, 2016; Packer R. J. et al.: J. Neurooncol., 121(1), 217-224, 2015; Zeng Z. et al,: Haematologica, 103(9), 1415-1417, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.