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Enarodustat hydrochloride

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SI-7524

Enarodustat hydrochloride, >98% (HPLC)

CAS No. : [1262131-60-1]

Synonyms : JTZ-951 hydrochloride; SAL-0951 hydrochloride

IUPAC Name : (7-Hydroxy-5-phenethyl-[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycine hydrochloride

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Chemical Properites
Mol. Formula :
C17H16N4O4 • HCl
Mol. Weight :
376.80
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Enarodustat hydrochloride inhibits HIF prolyl‑hydroxylase with sub‑micromolar potency (EC50= 0.22 µM), promoting HIF stabilization and erythropoietic responses. Its pharmacological profile supports its use in studies of renal anemia and hypoxia‑regulated pathways.

References : Ogoshi Y. et al.: ACS. Med. Chem. Lett., 8(12), 1320-1325, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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