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Encenicline hydrochloride

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SI-5662

Encenicline hydrochloride, >98% (HPLC)

CAS No. : [550999-74-1]

MDL No. : MFCD29049883

Synonyms : EVP-6124 hydrochloride

IUPAC Name : (R)-6-Chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride

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Chemical Properites
Mol. Formula :
C16H17ClN2OS . HCl
Mol. Weight :
357.29
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Encenicline hydrochloride is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). It is currently under development for addressing cognitive deficits associated with schizophrenia and Alzheimer's disease.

References : Prickaerts J. et al.: Neuropharmacology 62(2), 109, 2012; Papouin T. et al.: Neuron 94, 1-15, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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