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Encorafenib-13Cd3

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SI-5254

Encorafenib-13Cd3, >98% (HPLC)

Synonyms : LGX818-13Cd3

IUPAC Name : Methyl (S)-(1-(4-(3-(5-chloro-2-fluoro-3-((methyl)sulfonamido-13Cd3)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)propan-2-yl)carbamate

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Note: Encorafenib-13Cd3is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C2113CH23D3ClFN6O4S
Mol. Weight :
529.01
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Encorafenib-13C,d3 is a mixed 13C- and deuterium labelled version an analog of Encorafenib, which is a highly potent BRAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing BRAFV600E (EC50=4 nM). Encorafenib is used to treat unresectable or metastatic melanoma with specific mutations.

References : Li Z. et al.: Cancer Lett., 370(2), 332-44, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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