Entacapone EP impurity D

SL-4972

Entacapone EP impurity D, >98%

CAS No. : [857629-79-9]

IUPAC Name : (E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethylacrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is an impurity of Entacapone (Entacapone EP impurity D), which is an inhibitor of catechol-O-methyltransferase (COMT), used in the treatment of Parkinson's disease as an adjunct to Levodopa and Carbidopa therapy.

References : De Santi C. et al.: Eur J. Clin Pharmacol, 54(3), 215-219, 1998; .Di Giovanni S. et al.: J Biol Chem, 285(20), 14941-14954, 2010; Jenner P. et al.: Neurology, 62(1 Suppl 1), S47-55, 2004; Hamaue N. et al. Brain Res, 1309, 110-115, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.