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Entacapone impurity 2

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SL-4979

Entacapone impurity 2, >98%

IUPAC Name : 2,4-Dicyano-N1,N1,N5,N5-tetraethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)pentanediamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H29N5O6
Mol. Weight :
459.50
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Entacapone (Entacapone impurity 2), which is an inhibitor of catechol-O-methyltransferase (COMT), used in the treatment of Parkinson's disease as an adjunct to Levodopa and Carbidopa therapy.

References : De Santi C. et al.: Eur J. Clin Pharmacol, 54(3), 215-219, 1998; Di Giovanni S. et al.: J. Biol Chem, 285(20), 14941-14954, 2010; Jenner P. et al.: Neurology 62(1 Suppl 1), S47-55, 2004; Hamaue N. et al.: Brain Res, 1309, 110-115, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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