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Entecavir

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SI-6693

Entecavir, >98% (HPLC)

CAS No. : [142217-69-4]

Synonyms : BMS-200475; SQ-34676

IUPAC Name : 2-Amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one

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Chemical Properites
Mol. Formula :
C12H15N5O3
Mol. Weight :
277.28
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Entecavir is a highly potent and selective HBV inhibitor, demonstrating an EC50 of 3.75 nM in HepG2 cells. It is widely used to study HBV replication and nucleoside analog antiviral mechanisms.

References : Innaimo S. F. et al.: Antimicrob. Agents Chemother., 41(7), 1444-9, 1997; Rivkin A. et al.: Curr. Med. Res. Opin., 21(11), 1845-57, 2005; Genovesi E. V. et al.: Antimicrob. Agents Chemother., 42(12), 3209-18, 1998.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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