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Entecavir-d2

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SI-6694

Entecavir-d2, >98% (HPLC)

Synonyms : BMS-200475-d2; SQ-34676-d2

IUPAC Name : 2-Amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-(methylene-d2)cyclopentyl)-1,9-dihydro-6H-purin-6-one

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Chemical Properites
Mol. Formula :
C12H13D2N5O3
Mol. Weight :
279.3
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Entecavir‑d₂ is a deuterium-labelled version of Entecavir. The deuterated form is useful for analytical, metabolic, and tracer‑based investigations. Entecavir is a highly potent and selective HBV inhibitor. It is widely used to study HBV replication and nucleoside analog antiviral mechanisms.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Innaimo S. F. et al.: Antimicrob. Agents Chemother., 41(7), 1444-9, 1997; Rivkin A. et al.: Curr. Med. Res. Opin., 21(11), 1845-57, 2005; Genovesi E. V. et al.: Antimicrob. Agents Chemother., 42(12), 3209-18, 1998.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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