EP4 antagonist

SI-7081

EP4 antagonist, >98% (HPLC)

IUPAC Name : 4-((2-(4-Fluorobenzyl)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxamido)methyl)benzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This promising EP4 antagonist shows strong potency and excellent subtype selectivity with favorable drug‑like properties. It suppresses multiple immunosuppression‑related genes in macrophages and, when administered orally—either alone or combined with anti‑PD‑1—significantly enhances antitumor immunity and inhibits tumor growth in the CT26 colon carcinoma model.

References : Wang W. et al.: J. Med. Chem., 65(11), 7896-7917, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.