Epetraborole (R)-mandelate

SI-7392

Epetraborole (R)-mandelate, >98% (HPLC)

CAS No. : [1234563-15-5]

Synonyms : GSK-2251052 (R)-mandelate; AN-3365 (R)-mandelate

IUPAC Name : (S)-3-(Aminomethyl)-7-(3-hydroxypropoxy)benzo[c][1,2]oxaborol-1(3H)-ol (R)-2-hydroxy-2-phenylacetate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Epetraborole (R)‑mandelate inhibits leucyl‑tRNA synthetase with submicromolar potency (IC₅₀ = 0.31 µM), thereby disrupting aminoacyl‑tRNA formation and protein synthesis. It is applied in studies focused on multidrug‑resistant Gram‑negative bacterial pathogens.

References : Goldstein E. J. et al.: Antimicrob. Agents Chemother., 57(5), 2401-4, 2013;O'Dwyer K. et al.: Antimicrob. Agents Chemother., 59(1), 289-98, 2015; Sutcliffe J. A. Ann N. Y. Acad. Sci., 1241, 122-52, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.