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Epiminocycline

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Epiminocycline, >91% (HPLC)

CAS No. : [43168-51-0]

MDL No. : MFCD09840531

Synonyms : 4-Epiminocycline

IUPAC Name : (4R,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

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Chemical Properites
Mol. Formula :
C23H27N3O7
Mol. Weight :
457.48
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Epiminocycline is an impurity of Minocyclin, which is a second generation tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects.

References : Hu X. et al.: Eur. J. Pharmacol., 654(3), 274-279, 2011; Tao R. et al.: J. Cardiovasc Pharmacol., 56(6), 659-668, 2010; Padi S. S. et al.: Eur. J. Pharmacol., 601(1-3), 79-87, 2008; Brundula. V. et al.: Brain 125(Pt 6), 1297-1308, 2005; Tikka T. et al.: J. Neurosci., 21(8), 2580-2588, 2001.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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