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Eplerenone EP impurity F

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Eplerenone EP impurity F, >98%

CAS No. : [579484-30-3]

Synonyms : 9,11α-Epoxy-17-hydroxy-7α-(methoxycarbonyl)-3-oxo-17α-pregn-4-ene-21-carboxylic acid

IUPAC Name : 3-((4aS,4bR,5aR,6aR,7S,9aS,9bR,10R)-10-(Methoxycarbonyl)-4a,6a-dimethyl-2-oxo-2,3,4,4a,5a,6,6a,7,8,9,9a,9b,10,11-tetradecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)propanoic acid

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5MGRequest A Quote
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Chemical Properites
Mol. Formula :
C24H32O6
Mol. Weight :
416.51
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite or an impurity of Eplerenone (Eplerenone EP impurity F), which is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.

References : Kobayashi N. et al.: Hypertension 45(4), 538-544, 2005; Keidar S. et al.: J. Cardiovasc Pharmacol., 41(6), 955-963, 2003; Ward M. R. et al.: Circulation 104(4), 467-472, 2001; Suzuki G. et al.: Circulation 106(23), 2967-2972, 2002; Lacolley P. et al.: Circulation 106(22), 2848-2853, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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