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α-Epoxy abiraterone acetate

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α-Epoxy abiraterone acetate, >98%

CAS No. : [2484719-26-6]

IUPAC Name : (4S,6aR,6bS,8aS,8bR,9aR,10aS,10bR)-6a,8a-Dimethyl-8b-(pyridin-3-yl)-3,4,5,6,6a,6b,7,8,8a,8b,9a,10,10a,10b-tetradecahydro-1H-naphtho[2',1':4,5]indeno[1,2-b]oxiren-4-yl acetate

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C26H33NO3
Mol. Weight :
407.55
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Abiraterone, which is a potent, selective, and irreversible CYP17 inhibitor. Abiraterone is used in the treatment of prostate cancer.

References : Attard G. et al.: J. Clin. Oncol. 26(28), 4563-4571, 2008; Richards J. et al.: Cancer Res. 72(9), 2176-2182, 2012; Stein M. N. et al.: Asian J. Androl. 16(3), 387-400, 2014; Li R. et al.: Clin Cancer Res. 18(13), 3571-3579, 2012; Kumar S. V. et al. V. Biomed Chromatogr., 27(2), 203-207, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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