EPZ-015666

SI-6660

EPZ-015666, >98% (HPLC)

CAS No. : [1616391-65-1]

Synonyms : GSK-3235025

IUPAC Name : (S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : EPZ-015666 potently inhibits PRMT5 with an IC₅₀ of 22 nM and demonstrates oral activity, making it a valuable tool for probing PRMT5‑regulated epigenetic pathways.

References : Chan-Penebre E. et al.: Nat. Chem. Biol., 11(6), 432-7, 2015; Kryukov G. V. et al.: Science, 351(6278), 1214-8, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.