EPZ-020411 dihydrochloride

SI-6669

EPZ-020411 dihydrochloride, >98% (HPLC)

CAS No. : [2095432-47-4]

IUPAC Name : N1,N2-Dimethyl-N1-((3-(4-((1r,3r)-3-(2-(tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutoxy)phenyl)-1H-pyrazol-4-yl)methyl)ethane-1,2-diamine dihydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : EPZ-020411 hydrochloride selectively targets PRMT6 with low‑nanomolar potency (IC₅₀ = 10 nM) and demonstrates >10‑fold selectivity over PRMT1 and PRMT8. It serves as a valuable tool for studying PRMT6‑regulated transcriptional programs in cancer research.

References : Mitchell L. H. et al.: ACS. Med. Chem. Lett., 6(6), 655-659, 2019; Hua T. et al.: Brain Behav. Immun., 118, 101-114, 2024; Duan J. et al.: J. Immunother. Cancer, 13(3), e010639, 2025; He Y. et al.: Theranostics, 10(1), 133-150, 2020; Wang J. et al.: Cell Death Dis., 15(7), 524, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.