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Erlotinib-d6 hydrochloride

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Erlotinib-d6 hydrochloride, >98%

CAS No. : [1189953-78-3]

Synonyms : NSC 718781-d6; OSI-744-d6; R1415-d6

IUPAC Name : N-(3-Ethynylphenyl)-6,7-bis(2-(methoxy-d3)ethoxy)quinazolin-4-amine hydrochloride

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Chemical Properites
Mol. Formula :
C22H17D6N3O4 • HCl
Mol. Weight :
435.94
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Erlotinib, which is a potent, selective inhibitor of EGFR. Erlotinib is a targeted therapeutic agent indicated for the treatment of specific malignancies, most notably non-small cell lung cancer (NSCLC) and pancreatic cancer.

References : Ng S. S. et al.: Mol Cancer Ther., 1(10), 777-783, 2002; Moyer J. D. et al. Cancer Res., 57(21), 4838-48, 1997; Pollack V. A. et al.: J. Pharmacol Exp Ther., 291(2), 739-748, 1999.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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