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Ertugliflozin C4 epimer

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SL-6683

Ertugliflozin C4 epimer, >98%

CAS No. : [1210344-58-3]

IUPAC Name : (1S,2S,3S,4S,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

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Chemical Properites
Mol. Formula :
C22H25ClO7
Mol. Weight :
436.89
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Ertugliflozin, which is a potent and selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor, used to treat for the type 2 diabetes mellitus.

References : Meiyan J. et al.: Expert Opin Ther Pat., 25(11), 134, 2015; Mascitti V. et al.: J. Med. Chem.,54(8), 2952-60, 2011; Miao Z. et al.: Drug Metab Dispos., 41(2), 445-56, 2013; Kalgutkar A. S. et al.: Drug Metab Dispos., 39(9), 1609-19, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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