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Esmolol-d7 hydrochloride

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SL-8220

Esmolol-d7 hydrochloride, >98%

CAS No. : [1346598-13-7]

IUPAC Name : Methyl 3-(4-(2-hydroxy-3-((propan-2-yl-d7)amino)propoxy)phenyl)propanoate hydrochloride

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Chemical Properites
Mol. Formula :
C16H18D7NO4 . HCl
Mol. Weight :
338.88
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Esmolol, which is a cardioselective β1-adrenergic blocker with an ultra-short duration of action. It produces antiarrhythmic effects by activating the Neurokinin 1 Receptor. Esmolol also helps reduce myocardial dysfunction following resuscitation. In addition, it promotes diabetic wound healing by inhibiting aldose reductase, decreasing the formation of advanced glycation end products, and encouraging fibroblast migration. Researchers use Esmolol to investigate cardiac conditions such as arrhythmias and diabetic foot ulcers.

References : Kulkarni S. A. et al.: Front Endocrinol (Lausanne) 13, 926129, 2022; Wang L. L. et al.: Regul Pept., 186, 116-22, 2013; Zhang Q. et al.: PLoS One 8(12), e82677, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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