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Ethyl dolutegravir ring open impurity

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SL-7697

Ethyl dolutegravir ring open impurity, >98%

IUPAC Name : (R)-N-(2,4-Difluorobenzyl)-9-ethoxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide

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Chemical Properites
Mol. Formula :
C22H23F2N3O5
Mol. Weight :
447.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an analog of Dolutegravir, which is a second-generation HIV integrase strand transfer inhibitor (INSTI), used to treat HIV/AIDS.

References : Charpentier C. et al.: AIDS 24(17), 2753-275, 2010; Kobayashi M. et al.: Antimicrob Agents Chemother., 55(2), 813-21, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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