Etoposide-d4

SL-10582

Etoposide-d4, >98%

Synonyms : VP-16-213-d4; VP-16-d4

IUPAC Name : (5R,5aR,8aR,9S)-9-(((2R,4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-(methyl-d3)hexahydropyrano[3,2-d][1,3]dioxin-6-yl-2-d)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Etoposide-d4 is a deuterium labelled version of Etoposide. This can be used as an analytical labelled reference standard. Etoposide is an anti-cancer chemotherapeutic agent that acts by inhibiting topoisomerase II, thereby preventing DNA replication. Etoposide promotes cell cycle arrest, apoptosis, and autophagy in treated cells.

References : Lee K I. et al.: Toxicol In Vitro., S0887-2333(16), 30147-3, 2016; Calvani M. et al.: Oncotarget., 7(32), 51138-51149, 2016; Fuchs J. et al.: Cancer 83(11), 2400-7, 1998; Hande K. R. et al. Oncologist., 1(4), 234-239, 1996; Cui D. et al. Cell Rep., 30(2), 497-509.e4, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.