ETP-46464

SI-8170

ETP-46464, >98% (HPLC)

CAS No. : [1345675-02-6]

IUPAC Name : 2-Methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2H-[1,3]oxazino[5,4-c]quinolin-1(4H)-yl)phenyl)propanenitrile

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : ETP‑46464 inhibits mTOR with sub‑nanomolar potency (IC₅₀= 0.6 nM) and ATR with low‑nanomolar potency (IC₅₀ = 14 nM), making it a valuable tool compound for dissecting mTOR‑ and ATR‑dependent signaling networks.

References : Toledo L. I. et al.: Nat. Struct. Mol. Biol., 18(6), 721-7, 2011; Teng P. N. et al.: Gynecol. Oncol., 136(3), 554-61, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.